Vitamin D May Reverse Alzheimer’s Disease Amyloid Plaque Formation…

Scientists have discovered the mechanisms located inside the cells that are influenced and regulated by vitamin D3 according to a study published on the 6th of March in the Journal of Alzheimer’s Disease. This new research could probably solve the problem of amyloid plaques associated with Alzheimer’s disease. The study currently suggests that vitamin D3 could be responsible for the activation of genes and signaling networks that could influence the immune system to clear the amyloid proteins.

There have been earlier studies that suggested a link between vitamin D3, curcumin (also known as E100, a chemical substance found in Indian spices) and the stimulation of the immune system that led to clearing the amyloid proteins.

“This new study helped clarify the key mechanisms involved, which will help us better understand the usefulness of vitamin D3 and curcumin as possible therapies for Alzheimer’s disease”, said Dr. Milan Fiala, lead author of the study and researcher at University of California, Los Angeles (UCLA).

Scientists used the blood of healthy patients from the control group and patients that suffer from Alzheimer’s disease and isolated the immune cells that deal with the destruction of amyloid proteins. These cells are called macrophages and are in charge of clearing residual cells and other non-self particles from the body.

After the macrophages were isolated the team stored them in an enclosed space along with a quantity of amyloid.  1a,25–dihydroxyvitamin D3, which is one of the active forms of vitamin D3 was added to the mixture in order to see what effect it had on the consumption of amyloid.

Earlier research conducted by scientists has shown that patients with Alzheimer’s have two types of macrophages. The first type (called Type I macrophages) show an improved rate of consumption after adding curcuminoids along with 1a,25–dihydroxyvitamin D3, whilst the second type of macrophages (Type II macrophages) show an improved rate of consumption after adding only 1a,25–dihydroxyvitamin D3.

However, researchers have found that 1a,25–dihydroxyvitamin D3 has the important role of opening the chloride channel 3 (an important channel that supports the phagocytosis done by the macrophages. The addition of curcuminoids only affected the opening of this particular chloride channel in the Type I macrophages. Research also shows that 1a,25–dihydroxyvitamin D3 plays a very important role in the triggering of the transcription (the first stage of gene expression) of these particular chloride channels.

There are very complex mechanisms that stand behind the effects of 1a,25–dihydroxyvitamin D3 on phagocytosis, being dependent on calcium. With the help of Dr. Patrick R. Griffin and Dr. Mathew T. Mizwicki, the team of scientists have shown that 1a,25–dihydroxyvitamin D3 has a crucial effect, by using a method called mass spectrometry. They have shown that 1a,25–dihydroxyvitamin D3 has a greater effect than curcuminoids.

“Our findings demonstrate that active forms of vitamin D3 may be an important regulator of immune activities of macrophages in helping to clear amyloid plaques by directly regulating the expression of genes, as well as the structural physical workings of the cells”, said Dr. Mizwicki.

The team of scientists suggests that the next important step in the research would be to assess the impact of vitamin D3 on Alzheimer’s disease patients through a clinical trial. The also add that ongoing studies already show that vitamin D3 could also be beneficial in the case reduction of other diseases as well, not just Alzheimer’s disease.

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Read more: http://www.doctortipster.com/8434-vitamin-d-may-reverse-alzheimers-disease-amyloid-plaque-formation.html#ixzz2TCNQm7Jh

 

FUCOIDAN SEAWEED THE FUTURE OF CANCER TREATMENTS…

Can Fucoidan Seaweed Fight Cancer?

The latest buzz in the medical industry is that herbal foods such as seaweeds (also called sea vegetables) are regarded to be a great treatment for cancer patients and this topic has been attracting several scientists from around the world. Medical professional are extremely excited to have finally discovered the life-saving cancer cure from the ocean in the form of Fucoidan seaweed.

What is Fucoidan Seaweed?

For those of you, who are hearing the nameFucoidan seaweed for the first time, this is a complex polysaccharide (with anti-tumor properties) composed in huge part of natural sulfate and fucopyranoside that is seen in some brown seaweeds. Studies show that Fucoidal has a higher therapeutic potential, owing to the higher sulfate group counts in the plant.

Where is Fucoidan Seaweed Found?

Few of the seaweeds in which Fucoidan is seen in are limu, hijiki, mozuku, wakame, Kombu, and animals such as the sea cucumber. Researches have indicated that in Petrie dishes, it can cause specific kinds of quickly growing cancerous cells to self-destruct.

The Future of Cancer Treatment

Fucoidan seaweed has turned out to be the future of cancer treatment. And, this concept for cancer prevention or treatment dates back to as long as ancient Egypt. If you are wondering what’s so great about seaweeds, few facts indicate that the Egyptians in the ancient period used seaweeds for treating breast cancer even during the ancient times.

Herbal Foods Can Great Reduce the Cancer Occurrence

Fascinatingly, the postmenopausal women in Japan today experience just 1/9th the amount of breast cancer as against the United States women. The reason for such results is that the seaweeds form an important part of the Japanese diet right from ancient times. So, they also have the benefit of achieving the highest life expectancies.

There are several researches that have been carried out, and plenty of them are still being conducted using Fucoidan. The health benefits of this seaweed are amazing, as per the results of several recent studies.

Fucoidan Causes Cancerous Cells to Self-Destruct

The body triggers a natural process in the cell structure that renders the DNA blueprint useless. This helps the body to manage to get rid of the dangerous cells from the system, and all this can actually occur without harming the healthy and normal cells.

Several studies have proved that Fucoidan have caused self-destruction of cells in stomach, leukemia, colorectal, lymphoma, and breast cancers. Apart from its cancer healing and prevention effects, this substance is also known to strengthen the immune system significantly, while also helping to decrease the blood cholesterol levels. It is also effective in treating patients with meningitis.

Fucoidan Seaweed In a Nutshell

Fucoidan seaweed is the exciting future of treatment for the deadly disease, cancer. So, it may be a fantastic idea to include such herbal foods in your diet to rule out any possibilities of catching cancer, and similar life-threatening diseases in future.  http://berryripe.com/fucoidan-seaweed/

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Serrapeptase — an anti-inflammatory and pain reliever

by Dr. J. Michael Pece — 

Serrapeptase is a relatively new supplement that is gaining wide recognition among medical providers for its anti-inflammatory, pain relieving and fibrolytic (breaking down fibrin, scar tissue, atherosclerosis, etc.) effects.

The Serratia peptidase enzyme was discovered in the early 1970s in silkworm intestines. The silkworm uses this enzyme (Serratia E15 microorganism) to dissolve its protective cocoon without damaging living cells, allowing the silkworm to grow into a winged insect with the ability to fly away.

Researchers were looking for an alternative to the powerful anti-inflammatory agents and pain relievers such as aspirin, ibuprofen and the more potent NSAIDs. Serrapeptase is an anti-inflammatory, proteolytic enzyme isolated from the microorganism (Serratia E15) that has no inhibitory effects on prostaglandins, is devoid of gastrointestinal side effects and offers a sensible alternative to the above-mentioned pharmaceuticals. Serrapeptase is currently being produced in the laboratory through a fermentation process.

Serrapeptase is being used to treat many conditions. The list is long and contains many of society’s most common ailments, such as arthritis (both osteo and rheumatoid), fibrocystic breast disease, carpal tunnel syndrome and atherosclerosis. Researchers in Germany use Serrapeptase to digest atherosclerotic plaques without harming the healthy lining of the arterial wall.

Many researchers today consider atherosclerosis an inflammatory condition. Narrowing of the arteries results from inflammation and microscopic trauma in the presence of oxidized lipids. Serrapeptase does not interfere with the synthesis of cholesterol, but acts as an anti-inflammatory that clears plaques from the arterial wall. It can be an effective supplement for individuals undergoing EDTA chelation therapy.

As an anti-inflammatory, Serrapeptase has been used to treat many conditions, including chronic sinusitis, removal of bronchopulmonary secretions, sprains and torn ligaments, postoperative inflammation, to facilitate the therapeutic effects of antibiotics (a person can take lower doses of antibiotics), cystitis and epididymitis, and ligament damage due to trauma.

In a double-blind study, Serrapptase use was evaluated in a group of 70 patients with evidence of cystic breast disease. The patients were randomly assigned to a treatment group or a control group. Serrapeptase was noted to be superior to a placebo for treating breast pain, swelling and induration. More than 85 percent of the patients receiving Serrapeptase reported moderate to marked improvement with no adverse reactions.

In Europe, Serrapeptase has been used as a standard treatment for inflammatory conditions and traumatic swellings. In one study at the German State Hospital in Ulm, Germany, 66 patients treated surgically for fresh ruptures of the lateral ligament were divided into three random groups. One group received the test substance (Serrapeptase), while the two control groups used traditional treatments such as elevation of the leg and bed rest, with or without the application of ice.

In the group receiving the Serrapeptase, the swelling was reduced by 50 percent on the third postoperative day, while no reduction in swelling was noted for the two control groups. Also, the patients receiving Serrapeptase became pain-free more rapidly than the control groups. The therapeutic dose was one to two tablets (5 mg) three times a day.

Another study evaluated 193 subjects suffering from acute or chronic ear, nose or throat disorders. Treatment with 5 mg tablets of Serrapeptase lasted seven to eight days. After three to four days’ treatment, significant improvement was noted in the Serrapeptase group that was not indicated in the control group. Patients suffering from laryngitis, runny nose and sinusitis noticed markedly rapid improvement. More than 97 percent of physicians noted that the efficacy of the treatment with Serrapeptase was excellent or good, while only 22 percent of them rated the efficacy of the placebo as excellent or good.

Another area where Serrapeptase is beneficial is in the treatment of carpal tunnel syndrome. An effective treatment includes taking Serrapeptase and bromelain, along with vitamin B-2 (riboflavin) and B-6 (pyridoxin). These three supplements may help relieve the pain of carpal tunnel and similar repetitive stress injuries.

This brief overview of Serrapeptase is enough to indicate that it will likely be a major player in the years to come as a treatment for many of our modern illnesses. Perhaps the best news is that Serrapeptase is readily available; it can be found in many health food stores or is available from a naturopathic physician.

Dr. J. Michael Pece is a licensed naturopathic physician with a practice in Tempe Ariz. In his practice, he treats those with hepatitis, cancer, auto-immune disease, hormonal dysfunction and uses mesotherapy. 480-540-8838, drmike00@yahoo.com or http://www.calldrmike.com.

Reprinted from AzNetNews, Volume 25, Number 2, April/May 2006.

Where to purchase Serapeptase 

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Is Turmeric The Fountain Of Youth?

Turmeric is used as a spice, food additive, and in herbal medicine throughout the world. Its amazing medicinal properties, which include anti-cancer, anti-oxidant, anti-inflammatory capacities, are touted often, but could turmeric be the long-sought fountain of youth?

It turns out that active research on turmeric has demonstrated that curcumin and its active metabolite, tetrahydrocurcumin (THC) significantly increases the lifespan of the three following organisms:

 

1. Roundworms.  

Roundworms grown on media containing a low-dose of curcumin demonstrated an increased mean lifespan of 39%. The researchers attributed this increased lifespan to the reduction of reactive oxygen species.

2. Fruit flies. 

Fruit flies generally survive an average of 64 days, and in a study in which they consumed curcumin, their average lifespan increased to 80 days. In addition, the fruit flies exhibited higher levels of superoxide dismutase (SOD), a powerful antioxidant that defends the cells when they are exposed to oxygen.

 

3. Mice.

Male mice fed diets with curcumin beginning at the age of 13 months, lived on average, 84 days longer than mice who were not fed curcumin.

What does this mean for us?

Well, this is certainly promising data! Turmeric is easy enough to add to your diet – I recommend that you try to consume turmeric on a daily basis. Make it part of your daily routine and reap the benefits.

Here’s an easy turmeric tea recipe:

• Bring four cups of water to a boil.
• Add one teaspoon of ground turmeric and reduce to a simmer for 10 minutes.
• Strain the tea through a fine sieve into a cup, add honey and/or lemon to taste.

 Enjoy!

About Dr. Alejandra Carrasco

Alejandra Carrasco, M.D. is the founder of NOURISH , an innovative medical practice in Austin, TX that attends to all aspects of an individual’s life, including health, family, community, nutrition, exercise, stress reduction, self-care, and renewal.

 

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Astaxanthin—a Doctor’s Perspective

As a Health Professional, I’m thrilled that astaxanthin – one of the hottest ingredients on the market today – is getting the attention it deserves.

Over the last year-plus, it has been the subject of countless research studies, news articles and mainstream publicity thanks to the likes of Oprah Winfrey and Dr. Mehmet Oz, who raved about the benefits of astaxanthin on their talk shows.

This ingredient’s health benefits are plentiful: from its application to help alleviate the symptoms of hypertension and Type 2 Diabetes to more general health applications like cardiovascular support, eye fatigue relief, skin care and anti-aging protection, endurance and weight control, astaxanthin can be considered a one-size-fits-all approach to well-being.

Hypertension
Hypertension is a medical condition in which blood pressure in the arteries is elevated, requiring the heart to work harder than normal to circulate blood through the blood vessels. Hypertension is a major risk factor for stroke, myocardial infarction (heart attacks), heart failure, aneurysms of the arteries, peripheral arterial disease and is a cause of chronic kidney disease.

One of the main symptoms of hypertension is the thickening of the vascular walls, which reduces blood flow to the heart and increases systolic pressure. One research study showed that 5 mg of astaxanthin a day over a seven-week period reduced the thickness of the vascular wall by 47 percent.

In addition, recent studies have shown astaxanthin to help improve how the blood flows through the body, which can help reduce hypertension. One such study found that 6 mg of astaxanthin a day enhanced capillary blood flow by 10 percent – in only a ten-day period. Another study, conducted over a 30-day period, found that a 5mg a day dose of astaxanthin reduced systolic blood pressure (the measure of blood pressure while the heart is beating) by seven percent.

By improving the heart’s structure and reducing the amount of work needed to keep blood flowing, astaxanthin research is showing promising signs to help the heart work smarter, not harder.

Type 2 Diabetes
In people with type 2 diabetes – the most common form – the body does not produce enough insulin or the cells ignore the insulin, which is necessary for the body to be able to use glucose for energy. When you eat food, the body breaks down all of the sugars and starches into glucose, which is the basic fuel for the cells in the body. Insulin takes the sugar from the blood into the cells. When glucose builds up in the blood instead of going into cells, it can lead to diabetes complications.

New research into the effectiveness of astaxanthin preventing certain diabetes-related parameters has been promising. Studies have shown that eight weeks of astaxanthin usage can reduce cortisol levels by as much as 23 percent, expression of the lactic acid dehydrogenase (LDH) gene by 6.5 percent, and glycated hemoglobin molecules by 4 percent.

What does this mean? High cortisol levels can contribute to increased blood glucose and fat levels, markers for diabetes and pre-diabetes. LDH expression relates to the metabolism of glucose in the body, which is important for numerous organ functions when the genes are working properly. Overexpression of LDH can not only be a cause of concern for diabetes, but different forms of cancer (including testicular cancer, Ewing’s sarcoma, non-Hodgkin’s lymphoma, and some types of leukemia) and conditions such as heart failure, hypothyroidism and liver disease.

General Health Applications of Astaxanthin
Studied countless times for cardiovascular, vision, skin care and anti-aging benefits, astaxanthin has been proven to support and maintain your health in a variety of ways, from helping maintain normal cholesterol and blood pressure levels, to antioxidant protection, to muscle performance.

Research has shown that astaxanthin can help maintain normal cholesterol by protecting LDL (the bad kind of cholesterol) and triglyceride levels from free radicals through its powerful antioxidant defense. In addition, it works to maintain normal good cholesterol levels, or HDL, in the body.

Researchers conclude that for every 1 mg increase in good cholesterol HDL, the risk of cardiovascular diseases drops by three percent. A recent study found that astaxanthin users, over a 12-week trial, improved their HDL levels by as much as 11 percent.

Plus, astaxanthin has the ability to support healthy blood flow to and from the cardiac muscle. All of this helps to support your overall cardiovascular health.

For your vision, astaxanthin works to support healthy blood flow to the eyes — supporting visual focus and helping reduce the occurrence of occasional eye strain, helping the eyes to perform at their best. And, because of it efficacy, astaxanthin delivers more antioxidant power than any of the other carotenoids, displaying approximately 10 times the power of vitamin A.

One study found that individuals who received 5 mg of astaxanthin per day for one month showed a 54 percent reduction of eye fatigue complaints.

And that’s just scratching the surface. Astaxanthin has also been shown to:

• Support muscle endurance and performance
• Improve skin moisture and help to maintain skin elasticity
• Provide a powerful antioxidant defense to help protect the entire body on a cellular level

In Conclusion
There are more and more studies being released about the wonders of astaxanthin. As we continue to peel back the layers of this amazing ingredient, the health community is finding more quality benefits that are helping people live healthier, longer.

A final note: many studies are based on doses of six mg or more, so it is important – if you are investigating whether astaxanthin supplementation is right for you – to talk with your Health Professional about the type of astaxanthin available, including the serving amounts. It really does make a difference.

 

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Writen by Dr. Perry Krichmar

After graduating from SUNY Binghamton, Dr. Krichmar attended Long Island University where he obtained his master’s degree in biomedical sciences. He completed his internship and residency in Internal Medicine at Griffin Hospital in Derby, Conn. He is board certified in internal medicine and cardiology.

http://www.exploresupplements.com/astaxanthin%E2%80%94a-doctor%E2%80%99s-perspective

Natural sulforaphane compound from crucifers found effective to treat common form of leukemia…

(NaturalNews) Nutrition scientists have been proclaiming the health benefits of the bioactive compound, sulforaphane found in crucifers such as cauliflower and broccoli for the past 10 years. Prior research studies have concluded that the chemical directly alters the expression of our genes to lower the risk from many different types of cancer. It appears that mainstream medical science has finally caught on as studies are showing that the extracted compound can effectively treat one of the most aggressive and invasive forms of leukemia that primarily afflicts children.

A group of researchers at the Baylor College of Medicine in Texas has published the results of a study in the journal, PLoS ONE demonstrating that a concentrated form of the compound sulforaphane, found in broccoli and other cruciferous vegetables, has been shown to reduce the number of acute lymphoblastic leukemia cells in a lab setting. Lead study author, Dr. Daniel Lacorazza noted “Acute lymphoblastic leukemia is a type of cancer of the white blood cells common in children… there is about an 80 percent cure rate, but some children don’t respond to treatment. For those cases, we are in need of alternative treatments.”

Sulforaphane from broccoli and cauliflower regulates proteins needed for cancer cell proliferation

Past studies have shown that sulforaphane is effective in preventing and treating solid tumors, but no research to date has indicated that the vegetable-derived compound can provide an effective remedy to fight blood-borne cancers such as leukemia. To study the effectiveness of sulforaphane, the scientists incubated human-derived leukemic cell lines and primary lymphoblasts from pediatric patients with the compound. They found that the cancer cells died while the healthy cells obtained from healthy donors were unaffected.

The study team indicated that sulforaphane works by entering the cellular matrix and interacting with critical proteins that are needed for cancerous proliferation. They indicate that further work will be required to determine precisely which proteins are affected and the exact mechanism of action.

Dr. Lacorazza concluded “Sulforaphane is a natural product. However, what we used in this study is a concentrated purified form… so while eating cruciferous vegetables is good for you, it will not have the same effect as what we saw in the lab.” Eating crucifers regularly (three to four half-cup servings per week) and supplementing with a concentrated extract of sulforaphane provides a potent and natural shield against leukemia and many cancer lines.

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Learn more:  http://www.naturalnews.com/038363_sulforaphane_cruciferous_vegetables_leukemia.html#ixzz2FKNJKXU3

Sources for this article include:

http://www.plosone.org
http://www.bcm.edu/news/item.cfm?newsID=6615&r=1
http://www.sciencedaily.com/releases/2012/12/121212205602.htm

About the author:
John Phillip is a Certified Nutritional Consultant and Health Researcher and Author who writes regularly on the cutting edge use of diet, lifestyle modifications and targeted supplementation to enhance and improve the quality and length of life. John is the author of ‘Your Healthy Weight Loss Plan’, a comprehensive EBook explaining how to use Diet, Exercise, Mind and Targeted Supplementation to achieve your weight loss goal. Visit My Optimal Health Resource to continue reading the latest health news updates, and to download your Free 48 page copy of ‘Your Healthy Weight Loss Plan’.

Yerba Mate Benefits Causes Cancer Cells To Self Destruct…

Did you know…that bio-active compounds in yerba mate tea have been shown to cause cancer cells in the colon and liver to die?

Colorectal cancer is one of the leading causes of cancer-related deaths in the United States. One of the reasons colorectal cancer is so deadly is that it has no symptoms until the advanced stages—so it can be exceptionally difficult to diagnose.

However, when caught early enough, this cancer can be quite curable. Doctors recommend regular screening as a preventative measure, but what if you could simply kill any developing cancer cells from the comfort of your own kitchen?

According to a recent study conducted by scientists from the University of Illinois, one of the best possible ways to prevent colon cancer could be by drinking a cup of yerba mate tea.

What is Yerba Mate?

Yerba mate is made from the leaves of a tree (Ilex paraguariensis) native to South America. The people indigenous to that region have long been aware of yerba mate benefits for medicinal applications. Now, researchers worldwide are beginning to investigate—and confirm—the tea’s healing powers.

Stopping Colon Cancer at Its Cellular Source

The University of Illinois study is just one exciting example of scientific validation of yerba mate benefits.

Elvira de Meja, an associate professor of food chemistry and food toxicology at the University, headed the research team. For the study, de Meja and her colleagues isolated and purified caffeine derivatives—including caffeoylquinic acid, or CQA—of yerba mate tea.

The team then used those derivatives to treat colon cancer cells in vitro (in a laboratory vessel, such as a test tube). As the team increased the concentration of CQA, cancer cells began to die away as the result of a process known as apoptosis.

“Put simply, the cancer cell self-destructs because its DNA has been damaged,” de Meja explains. She and her fellow scientists believe yerba mate benefits induce apoptosis and cancer cell death makes it a promising treatment option for all types of cancer.

The results of de Meja and her team’s work were published in Molecular Nutrition & Food Research in 2011. Considering the implications of those results, more inquiries into yerba mate benefits potential as an anti-cancer weapon are sure to be forthcoming.

Fighting Cancer by Reducing Inflammation

Not only do the caffeine derivatives from yerba mate benefits kill cancer cells, but they also reduce cellular inflammation. Inflammation can trigger cancer’s onset and progression. The tea’s anti-inflammatory capabilities are one of the major reasons de Meja sees it as such a viable cancer-fighting agent.

Benefits Include Heart Health, Fat Loss, and More

In addition to fighting cancer, yerba mate benefits potent caffeine derivatives may be helpful in combating other disease associated with inflammation. And separate studies have also suggested a host of other benefits obtained from drinking yerba mate, showing that it…

• Reduces oxidative stress on the heart and liver
• Protects DNA from damage
• Kills liver cancer cells in humans
• Improves the flow of blood
• Lowers risk of heart disease
• Reduces fat accumulation

90% More Antioxidants than Green Tea

Aside from the caffeine derivatives, yerba mate benefits are rich in several important vitamins, minerals, and antioxidants. Some blends of yerba mate have 90% more antioxidants than green tea. Some of the other significant compounds found in yerba mate include:

• B vitamins
• Vitamin C
• Potassium
• Zinc
• Quercetin
• Theobromine
• Theophylline

A Beginner’s Guide to Drinking Yerba Mate (Just One Cup Kills Cancer Cells!)

When prepared traditionally, it is brewed and served in a hollowed-out gourd. A metal straw with a filter on one tip is used to prevent drinkers from sucking up the leaves.

The tea is available in a more convenient, pre-bagged form at most health food stores. It can be found at some of the larger supermarkets as well.

The beverage’s flavor is typically described as smoky…bitter…and woody, which may explain why many American consumers have had to acquire the taste.

If the first sip doesn’t go down smoothly, just think of all the disease-fighting powers you’re drinking in. When you remember that yerba mate benefits far outweigh the effort it takes to tolerate the taste, the medicine goes down more easily.

The University of Illinois study showed that the concentration of bio-active compounds contained in just one cup of yerba mate tea is sufficient to kill off colon cancer cells.

“We believe there’s ample evidence to support drinking yerba mate tea for its bio-active benefits,” says de Meja.   Read more: http://undergroundhealthreporter.com/yerba-mate-benefits#ixzz2CJYQTsZ8

 
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